Ultimate 2-Day Milan Itinerary: Best Things to Do & See in 48 Hours

Ultimate 2-Day Milan Itinerary: Best Things to Do & See in 48 Hours

Every guide is crafted with love, real research, and carefully chosen photos that show what each destination actually looks like. Thank you for exploring with me. - Narmin (Read more)

Milan, Italy's fashion and design capital, is a city where history, culture, and modernity intertwine effortlessly. With just two days to explore, you'll want to make the most of your time by visiting the iconic landmarks, hidden gems, and savoring the city's vibrant atmosphere. Whether you're a first-time visitor or a seasoned traveler, Milan offers an unforgettable experience that will leave you enchanted.
Here’s how to plan the perfect two-day itinerary in Milan, divided into morning, afternoon, and evening to ensure you enjoy the best of this elegant city:

Milan, aerial view of Sempione park - a lush green oasis in the heart of the city, framed by historic landmarks like Sforza Castle and the Arch of Peace, offering a peaceful escape amidst Milan’s urban energy/Depositphotos
Disclosure: This post contains affiliate links, which means I may earn a small commission if you make a purchase or booking through them-at no extra cost to you. I only recommend products and services I’ve personally used and loved, or those I’ve thoroughly researched and genuinely trust to share with you.

Day 1: Milan’s Iconic Sights

Begin your Milan adventure with a visit to the Duomo di Milano, one of the world’s most magnificent cathedrals. Standing tall in the heart of the city, the Duomo is a masterpiece of Gothic architecture, and its rooftop offers panoramic views of Milan. Whether you choose to climb the stairs or take the elevator, the sight of the city from above is truly mesmerizing. 

Milan, magnificent exterior of Duomo di Milano – a stunning display of Gothic architecture with marble spires, delicate carvings, and the golden Madonnina shining atop the tallest pinnacle/Depositphotos
Milan, magnificent interior of Duomo di Milano – an awe-inspiring space filled with towering columns, vibrant stained glass windows, and sacred art bathed in soft, ethereal light/Depositphotos

Afterward, stroll through the nearby Galleria Vittorio Emanuele II, an exquisite 19th-century shopping gallery. The glass-roofed arcade is home to high-end boutiques, elegant cafés, and a perfect spot for a morning coffee while soaking in the Milanese atmosphere.

Milan, mosaic floor and glass dome in Galleria Vittorio Emanuele II – a stunning blend of art and architecture with intricate marble mosaics underfoot and a soaring iron-and-glass dome above, exuding timeless elegance/Depositphotos

Next, head to Sforza Castle (Castello Sforzesco), a historical fortress located in the city’s center. Once home to Milan’s ruling families, the castle now houses a collection of museums and art galleries. Take a leisurely walk through the castle grounds, visit the Sforza Castle Museum, or discover the impressive Museum of Ancient Art. 

Milan, Sforza Castle aerial panoramic view – a grand Renaissance fortress surrounded by lush Sempione Park, revealing its majestic courtyards, red-brick towers, and centuries of Milanese history from above/Depositphotos

Afterward, unwind in Parco Sempione, the green lung of Milan, located right behind the castle. Enjoy a peaceful moment by the pond or take in the majestic Arch of Peace (Arco della Pace) as you stroll through the park.

Milan, Sempione Park near Sforza Castle – a peaceful green escape with tree-lined paths, tranquil ponds, and iconic views of the castle and Arco della Pace/Depositphotos
Milan, Arch of Peace in the background, with a vintage yellow tram passing through – a perfect blend of historic grandeur and everyday charm, capturing the city’s timeless elegance in motion/Depositphotos

As evening falls, head to the Navigli District, one of Milan’s most picturesque neighborhoods. Known for its charming canals and vibrant nightlife, the Navigli area is perfect for an evening walk. Stop by one of the local bars for an aperitivo, a Milanese tradition of pre-dinner drinks paired with small bites. The canal-side ambiance, with its reflections of old buildings and lights, creates a truly magical atmosphere. Finish the night with a traditional Milanese dinner at a nearby trattoria, where you can try the classic Risotto alla Milanese or Cotoletta alla Milanese.

Milan, people relax at a restaurant terrace in the popular Navigli district – lively canalside vibes with clinking glasses, cozy lights, and the buzz of locals and travelers enjoying aperitivo by the water/Depositphotos

Day 2: Art, Culture, and Fashion

Start your second day with one of Milan’s most famous art treasures, The Last Supper (Cenacolo Vinciano) by Leonardo da Vinci. Located at Santa Maria delle Grazie, this iconic masterpiece is a must-see. Make sure to book tickets in advance, as they tend to sell out quickly. 

Santa Maria delle Grazie, interior – a serene blend of Gothic elegance and Renaissance harmony, with vaulted ceilings, soft light filtering through arched windows, and a sacred calm surrounding Da Vinci’s masterpiece/Depositphotos
Milan, The Last Supper painting by Leonardo da Vinci – a masterpiece of Renaissance art capturing the dramatic moment of Christ’s final meal, housed in the refectory of Santa Maria delle Grazie/Depositphotos

Afterward, head to the Pinacoteca di Brera, one of Milan’s most renowned art galleries. The collection includes works by legendary artists such as Caravaggio, Raphael, and Titian, offering a deep dive into Italy’s rich artistic heritage.

Milan, Brera Art Gallery – a cultural gem housed in a historic palace, showcasing Italian masterpieces by Caravaggio, Raphael, and Mantegna in an elegant, contemplative setting/Depositphotos

No trip to Milan is complete without indulging in some shopping, and the Quadrilatero d’Oro (Golden Rectangle) is the place to do it. Milan is the fashion capital of the world, and this luxury shopping district, with streets like Via Montenapoleone, is home to the most exclusive boutiques and high-end brands. Even if shopping isn't on your agenda, window-shopping is an experience in itself. Take a break and enjoy lunch in the Brera district, a charming area filled with quaint cafes and traditional Italian eateries, offering everything from fresh pasta to delicious pastries.

Milan, historical buildings and boutique shops on Via Montenapoleone – a glamorous avenue where neoclassical façades meet high fashion, offering a chic stroll through the heart of Milan’s luxury district/Depositphotos

To conclude your Milan adventure, immerse yourself in the world of opera and ballet at the Teatro alla Scala, one of the most famous opera houses in the world. Check the schedule for performances and enjoy a night of cultural refinement. For a relaxed end to the day, head to Brera or Porta Romana for another aperitivo or a cozy dinner. Milan’s nightlife offers a variety of options, from trendy cocktail bars to intimate wine shops, where you can reflect on your unforgettable Milan experience.

Milan, Teatro alla Scala panoramic view – an iconic opera house with a neoclassical façade, rich cultural legacy, and a grand piazza that echoes the elegance of Milanese performing arts/Depositphotos
Milan, typical street in Brera neighborhood – charming cobblestone lanes lined with ivy-draped buildings, art galleries, and cozy cafés, capturing the bohemian soul of Milan/Depositphotos

Final thoughts:
Milan may be known for its high fashion and design, but it offers so much more—from world-class art and history to delightful cuisine and charming neighborhoods. This two-day itinerary is designed to help you experience the very best of Milan, balancing iconic attractions with hidden gems. Whether you’re marveling at Leonardo da Vinci’s genius, shopping in the fashion capital, or enjoying an evening along the canals, Milan will leave you with memories to treasure for a lifetime.

We Recommend:

For Hotels & Bundles: Expedia
For Tours: GetYourGuide
Back to blog